No big surprise, the SART grading categories are highly correlated to success:
Good is considered AA or AB. Fair is considered BA, BB, or BC. Poor is considered CB or CC.
In this article, over 60% of “good” embryos implanted, and over 50% resulted in a live birth. Just under 50% of “fair” embryos implanted, with over 35% resulting in live birth. They had few data points for the “poor,” but none of them worked. (I’ve read some clinics will not freeze poor quality embryos because of their low chance of success.) Now I’m re-thinking my guesses at what my embryos were rated. My lab says it has at least an 18% pregnancy rates with B3s, which suggests B3s are better quality than CC. Maybe BC. (http://3yearwait.blogspot.com/2015/11/blastocyst-grading-no-students-here.html)
Here’s another one that breaks it down further:
“From the results, the pregnancy rates of AA, BA, AB, and BB for patients <30 years of age were similar and there were no significant differences. The pregnancy rates of AA, BA, and AB tended to be higher than that of BB for patients 30-34 years of age, and this tendency was observed for the patients 35-39 years of age.”
“The pregnancy rates of blastocyst grading AA, BA, AB, and BB for the patients who were more than 40 years of age were 61.9, 54.5, 38.7, and 17.6%, respectively.”
So if you’re young, anything with an A or a B will do. If you’re old, you definitely want As, and all Bs are bad news.
Okay, and here’s an article that suggests, unsurprisingly, that better-quality embryos were more likely to be chromosomally normal:
Blastocyst grade
|
AA
|
AB
|
BA
|
BB
|
Chromosomally normal
|
62%
|
41%
|
62%
|
33%
|
They also give you a chart regarding which one you should choose. Basically AA = BA > AB > BB
I would be interested in knowing what my embryos would be considered rated using these standards.
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