Thursday, February 26, 2015

Miscarriage Risk

I wasn’t planning on posting again until I had a heartbeat appointment, but I found a cool / terrifying website that collects medical journal articles on miscarriage risks / factors.  Right up my alley!
The website summarizes the medical journal articles, and I’ll summarize the website’s summaries. (Although here's a nice summary from the website: https://sites.google.com/site/miscarriageresearch/what-causes-miscarriage)
Things you can (theoretically) control that have been shown to help fertility/decrease miscarriage risk:
·        Eat chocolate.  :)
·        Eat good fats (olive oil).  
·        Eat whole milk, yogurt, ice cream, and cheese.
·        Eat eggs.
·        Eat fiber (whole grains, veggies, certain fruits).
·        Eat fruit.  (“Eating 2+ servings of fruit per day lowers risk of miscarriage by 70%.”) 
·        Eat veggies.
·        Eat fish.
·        Moderate exercise is okay/good.
·        Multivitamins are good.  (Pretty much all vitamins are good, including DHEA.)
·        Gluten free is good… if you have celiac disease.

·        Don’t drink when TTC.  (This one made me sad because l love my booze.)  Drinking makes it more likely you’ll have a short luteal phase (luteal phase defect!), and decreases pregnancy and live birth rate.   :(
·        Don’t eat a lot of butter or oil.  
·        Don’t eat bad fats (cake).
·        Don’t be fat.
·        Strenuous exercise is bad.
Things your hubby/boyfriend/sperm donor can do that have been shown to help fertility/decrease miscarriage risk:
·        Eat cereal, fruit, folate, fish.
·        Don’t drink.
·        Don’t be fat.  And also don’t diet.  (Damned if you do, damned if you don’t.)
·        Don’t eat (too much?) red meat.
·        Don’t smoke.
It also provides general miscarriage statistics:
Event
Miscarriage risk
Overall
17-22%
Gestational sac
12-15%
Heartbeat 6 wks
9.4%
Heartbeat 7 wks
4.2%
Heartbeat 8 wks
1.5%
Heartbeat 9 wks
0.5%
Heartbeat 10 wks
0.7%
Second trimester
0.5%

Other factors relating to miscarriage risk:
·        Miscarriage risk increases 12% after (mom) age 30; goes up 39% after age 35; doubles after age 40
·        Miscarriage risk increases after (mom) age 35; increases 5 fold after age 40
·        Miscarriage risk doubles after (mom) age 40 and triples after age 45
·        Having a partner (dad) over 40 years old increases risk of miscarriage by 60%
·        Risk of miscarriage increases by 43% when partner (dad) is age 35, by 90% at age 50
·        Miscarriage risk increases 88% if the father is over 50 years old
·        Miscarriage risk doubles for those who need more than a year to successfully conceive (boo!)
·        Induced abortion increases the risk of miscarriage 128% for up to 2 years
We already knew this one:
·        Morning sickness associated with 70% reduction in miscarriage risk, with a marked increasing trend of reducing odds with increasing severity of nausea.
And here are a few real bummers for those of us with recurrent miscarriages:
·        Recurrent miscarriage increases risk of stillbirth 1300%, preterm birth 60%, ectopic pregnancy 160%
·        Miscarriage risk is normally 2% after a heartbeat is seen; but 18% in women with recurrent miscarriage
·        Risk of miscarriage only increases by 7% after one loss; nearly doubles after three or more
·        After two miscarriages, one still has a 91.2% chance of successful pregnancy; drops to 20% after 7.  In other words, the most miscarriages you’ve had, the more likely you are to have another one:

Previous number of miscarriages
2
3
4
5
6
7
Live birth rate for 1stpregnancy after exam
76.3%
66.1%     
59.0%     
53.3%    
31.3%      
13.3%
Cumulative success rate (birth of at least 1 child)
91.2%      
82.9%     
76.0%     
73.3%    
56.3%      
20.0%







·        Each miscarriage raises risk of future heart attack by 40%
I have not read any of the underlying studies.  Like, for the last one, did it account for obesity?  I mean, is it possible that being obese was a risk factor for infertility (it is) and heart attack (it is), but that infertility alone has no connection to heart attack?  I hope so!
Okay, here a few more:
·        Supplemental progesterone decreases miscarriage risk after unexplained recurrent miscarriages.
Anyway, after I read this I ate a bowl of strawberries, and was happy I had some chocolate today, but regretted the pizza I had for dinner… and breakfast.

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